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EC number: 400-820-2
CAS number: 84268-33-7
None of the animals died during the study. Clinical signs observed
during the study included: sedation, dyspnoea, exophthalmus, ruffled fur
and curved body posture. These signs were slight in their severity and
occurred from 1 hour post-dosing to day 10.
There were no effects on the organs and no treatment-related gross
pathological effects were noted.
In an acute oral toxicity test performed using the standard acute method
(method B1 of Annex V), under the conditions of GLP, the acute oral
median lethal dose (LD50) of the substance in the male and female rat
was determined to be greater than 5000 mg/kg bodyweight. Signs of
sedation, exophthalmus, fuffled fur and curved body posture were noted
during the study. These effects were all considered to be of slight
severity and occured from 1 hour post dosing to day 10 but no gorss
pathological efects were noted.
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