Registration Dossier
Registration Dossier
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EC number: 201-178-4 | CAS number: 79-11-8
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Secondary source only
Data source
Referenceopen allclose all
- Reference Type:
- secondary source
- Title:
- Chloroacetic acid, CAS No: 79-11-8
- Author:
- OECD SIDS
- Year:
- 1 996
- Bibliographic source:
- http://www.inc hem.org/doc uments/sids/s ids/79118.pdf
- Reference Type:
- publication
- Title:
- Empirical determination of the MAC value for chloracetic acid in production plant atmospheres
- Author:
- Maksimov, G.G. and Dubinina, O.N.
- Year:
- 1 974
- Bibliographic source:
- Labour Hygiene and Occupational Diseases, 18, 32
Materials and methods
- Principles of method if other than guideline:
- The test substance was instilled into the eyes of rabbits to evaluate eye irritation.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Chloroacetic acid
- EC Number:
- 201-178-4
- EC Name:
- Chloroacetic acid
- Cas Number:
- 79-11-8
- Molecular formula:
- C2H3ClO2
- IUPAC Name:
- chloroacetic acid
- Details on test material:
- - Name of test material (as cited in study report): Chloracetic acid
- Analytical purity: no data
Constituent 1
Test animals / tissue source
- Species:
- rabbit
- Strain:
- not specified
Test system
- Amount / concentration applied:
- 100% solution
Results and discussion
In vivo
- Irritant / corrosive response data:
- The test substance was highly irritating as concentrated solution as sever conjunctival burns were determined in test animals.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
