Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2002
Report date:
2002

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 402 (Acute Dermal Toxicity)
Deviations:
not specified
GLP compliance:
yes
Test type:
standard acute method

Test material

Constituent 1
Chemical structure
Reference substance name:
2,6-dichloro-4,8-dipiperidinopyrimido[5,4-d]pyrimidine
EC Number:
230-437-4
EC Name:
2,6-dichloro-4,8-dipiperidinopyrimido[5,4-d]pyrimidine
Cas Number:
7139-02-8
Molecular formula:
C16H20Cl2N6
IUPAC Name:
2,6-dichloro-4,8-dipiperidinopyrimido[5,4-d]pyrimidine

Test animals

Species:
rabbit
Strain:
New Zealand White
Sex:
male

Administration / exposure

Type of coverage:
not specified
Vehicle:
not specified

Results and discussion

Effect levels
Sex:
male
Dose descriptor:
LD50
Effect level:
> 2 000 mg/kg bw
Based on:
not specified

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
The dose tested during the experimentation period of fourteen days did, not cause any death or any type of cutaneous irritation visually detectable.