Registration Dossier
Registration Dossier
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EC number: 700-340-6 | CAS number: 76524-94-2
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Not readily biodegradable: 46% in 28 days (CO2 evolution) (OECD 301B)
Key value for chemical safety assessment
Additional information
The biodegradation behavior of Y-15864 (CAS 76524-94-2) was investigated in a key study (Eisner, 2012). The study was performed according to OECD Guideline 301 B under GLP conditions. Activated sludge from a wastewater treatment plant was used as inoculum. Activated sludge microorganisms were exposed to a test substance concentration of 30.5 mg/L under aerobic conditions for 28 d. The result indicated that the test substance reached a mean degradation of 46% (CO2 evolution). The pass level of at least 60% biodegradation in a 10-day window was not reached. Therefore, the test substance is not readily biodegradable according to the OECD criteria. The toxicity control reached 60% biodegradation within 14 days of exposure and 67% after 28 d. The test item had no inhibitory effect on activated sludge microorganisms at the tested concentration of 31 mg/L because biodegradation in the toxicity control was≥ 25% within 14 days of incubation.
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