Registration Dossier
Registration Dossier
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EC number: 401-990-0 | CAS number: 106990-43-6 CHIMASSORB 119; LOWILITE 19
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: information from migrated NONS file as per inquiry # [06-0000014790-71-0000], permission to refer granted by ECHA
Data source
Reference
- Reference Type:
- other: body responsible for the test
- Title:
- Unnamed
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: OECD guideline 402 Annex V B3
- GLP compliance:
- yes
Test material
- Reference substance name:
- N,N',N'',N'''-tetrakis(4,6-bis(butyl-(N-methyl-2,2,6,6-tetramethylpiperidin-4-yl)amino)triazin-2-yl)-4,7-diazadecane-1,10-diamine
- EC Number:
- 401-990-0
- EC Name:
- N,N',N'',N'''-tetrakis(4,6-bis(butyl-(N-methyl-2,2,6,6-tetramethylpiperidin-4-yl)amino)triazin-2-yl)-4,7-diazadecane-1,10-diamine
- Cas Number:
- 106990-43-6
- Molecular formula:
- C132H250N32
- IUPAC Name:
- N,N',N'',N'''-tetrakis(4,6-bis(butyl-(N-methyl-2,2,6,6-tetramethylpiperidin-4-yl)amino)triazin-2-yl)-4,7-diazadecane-1,10-diamine
Constituent 1
Test animals
- Species:
- other: Rat, KFM-Han, wistar (outbred, SPF quality)
Administration / exposure
- Vehicle:
- other: Distilled water containing 4% carboxymethylcellulose sodium salt
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Mortality:
- Male: 2000mg/kg bw; number of animals: 5; number of deaths:0
Female: 2000mg/kg bw; number of animals: 5; number of deaths:0 - Gross pathology:
- Effects on organs: No macroscopic organ changes were observed.
- Other findings:
- Signs of toxicity (local): All the male rats showed a slight erythema at day 2, but recovered within 5 days.
All the females rats showed a slight erythema at day 3 until terminatioon of observation.
Applicant's summary and conclusion
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Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
