Registration Dossier

Administrative data

Description of key information

In an acute oral toxicity study in rats according to a method similar or equivalent to EU method B.1 and OECD guideline 401 the LD50 was determined to be 1410 mg/kg bw for males and 1620 mg/kg bw for females. In an acute inhalation study in rats according to EU method B.2 and OECD guideline 403 the 4 hour LC50 was determined to be > 21.3 mg/L. In an acute dermal toxicity study in rats according to EU method B.3 and OECD guideline 402 to LD50 was determined to be > 2000 mg/kg bw.

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
LD50
Value:
1 410 mg/kg bw

Acute toxicity: via inhalation route

Endpoint conclusion
Dose descriptor:
LC50
Value:
21 300 mg/m³

Acute toxicity: via dermal route

Endpoint conclusion
Dose descriptor:
LD50
Value:
2 000 mg/kg bw

Additional information

Justification for classification or non-classification

Based on the data available the substance is classified and labeled Xn; R22 Harmful; Harmful if swallowedaccording to Directive 67/548/EEC (DSD) and Acute Tox. 4 H302: Harmful if swallowed according to Regulation 1272/2008/EC (CLP).