Registration Dossier

Administrative data

Endpoint:
eye irritation: in vivo
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
1992
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Secondary source (ECB); according to OECD Guideline 405 and GLP.

Data source

Reference
Reference Type:
secondary source
Title:
Unnamed
Year:
1992
Report Date:
2000

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 405 (Acute Eye Irritation / Corrosion)
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals / tissue source

Species:
rabbit
Strain:
not specified

Test system

Vehicle:
not specified

Results and discussion

In vivo

Resultsopen allclose all
Irritation parameter:
cornea opacity score
Score:
0
Irritation parameter:
iris score
Score:
0
Irritation parameter:
conjunctivae score
Score:
1.44
Irritation parameter:
chemosis score
Score:
1

Applicant's summary and conclusion

Interpretation of results:
not irritating
Remarks:
Migrated information