Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 253-057-0 | CAS number: 36483-57-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
Hydrolysisas a Function of pH
Key value for chemical safety assessment
- Half-life for hydrolysis:
- 2 720 d
- at the temperature of:
- 25 °C
Additional information
FR-513 was determined to be hydrolytically stable across the range of environmentally relevant pH at 25°C. The half-life of FR-513 at pH 4 and 7 was estimated to be greater than 1 year as determined by 5-day incubations at 50 °C. FR-513 was found to be hydrolytically active only in pH 9 aqueous buffer at elevated temperatures. Definitive testing at three elevated temperatures (40, 50 and 60 °C) showed a very strong temperature dependence of FR-513 hydrolysis at pH 9. Two hydrolytic degradants - DBMO and bromide - were detected and measured. Using the Arrhenius equation and the results from these elevated temperatures, the calculated hydrolysis rate constant for FR-513 at pH 9 and 25°C was extrapolated as 2.55 x 10-4 day-1, corresponding to a half-life of 2.72 x 103 days (approximately 7.5 years).
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