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EC number: - | CAS number: -
Tables and figures of the Pre-screen test and Main study have been included in the attached document "LLNA tables and figures".
Results Pre-screen test:
Purple staining by the test substance prevented scoring for erythema. As no signs of necrosis or oedema were present, a 25% concentration was selected as the highest concentration that could be used in the main study.
Other results - main study:
Skin reactions / Irritation: No irritation of the ears was observed in any of the animals examined. Purple staining by the test substance prevented scoring for erythema on the test substance treated animals. No oedema was observed in any of the animals examined.
Macroscopy: All auricular lymph nodes of the animals of the experimental and control groups were considered normal in size. No macroscopic abnormalities of the surrounding area were noted in any of the
Body weights: Body weights and body weight gain of experimental animals remained in the same range as controls over the study period. The slight body weight loss, noted in some animals, was considered not
Toxicity and mortality: No mortality occurred and no symptoms of systemic toxicity were observed in the animals of the main study.
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