Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Study period:
1999
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: OECD 107 Test under GLP

Data source

Reference
Reference Type:
publication
Title:
Unnamed
Year:
1999
Report Date:
1999

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
Deviations:
no
GLP compliance:
yes
Type of method:
shake-flask method to: flask method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
-0.69
Temp.:
21 °C
pH:
> 6.3 - < 6.5

Applicant's summary and conclusion

Conclusions:
Based on an experimental n-octanol/water partition coefficient, L-Pantolactone is not expected to partition
significantly to organic phases or tissues, but rather to remain in aqueous phases.