Registration Dossier

Administrative data

Key value for chemical safety assessment

Additional information

Ames test, Salmonella thyphi. (TA98, TA100, TA1535, TA1537, TA1538): negative

Sister-chromatid exchange (SCE) in vitro : positive

Chromosome aberration: positive

Mouse male, Sperm morphology: positive



Short description of key information:
Reference:
EMICBACK/21338; PROC NATL ACAD SCI USA 72:5135-5139,1975
EMICBACK/45337; MUTAT RES 101:165-172,1982
EMICBACK/48093; MUTAT RES 99:273-291,1982
EMICBACK/50126; MUTAT RES 115:1-72,1983

Endpoint Conclusion: Adverse effect observed (positive)

Justification for classification or non-classification