Registration Dossier

Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Referred in a recognized source of peer reviewed scientific data on chemicals

Data source

Reference
Reference Type:
review article or handbook
Title:
Toxicological Profile for Total Petroleum Hydrocarbons (TPH)
Author:
ATSDR
Year:
1999
Bibliographic source:
ATSDR September 1999.

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: Acute Dermal exposure
Principles of method if other than guideline:
Acute Dermal exposure
GLP compliance:
not specified
Test type:
other: Acute Dermal exposure

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
Paraffin oils/waxes

Results and discussion

Any other information on results incl. tables

Study results:

 

No mortality or clinical signs of toxicity were observed

 

LD0 (rabbit, dermal) = 2000 mg/kg bw;

LD50 (rabbit, dermal) > 2000 mg/kg bw

Applicant's summary and conclusion

Conclusions:
LD0 (rabbit, dermal) = 2000 mg/kg bw;
LD50 (rabbit, dermal) > 2000 mg/kg bw