Registration Dossier

Environmental fate & pathways

Biodegradation in water: screening tests

Administrative data

Endpoint:
biodegradation in water: ready biodegradability
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: US EPA accepted QSAR method for organic chemicals properties assessment.
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
2009

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: QSAR
Principles of method if other than guideline:
BIOWIN v4.10
GLP compliance:
no
Remarks:
not applicable to QSAR models

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
Mineral Paraffin Oil is a complex UVCB substance. Data for components.

Results and discussion

Any other information on results incl. tables

Overview of estimated data for biodegradation ofMineral Paraffin Oilcomponents in water

Method

 

Results

Remarks

Reference

Pentadecane, C15H32(CAS No. 629-62-9)

 

QSARs

Biodegrades Fast

Predicted with BIOWIN1 (Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN2 (Non-Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Days -Weeks

Predicted with BIOWIN3 (Ultimate Biodegradation Timeframe)

EPI Suite

(v.4.00) software

QSARs

Days

Predicted with BIOWIN4 (Primary Biodegradation Timeframe)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN5 (MITI Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN6 (MITI Non-Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Does Not Biodegrade Fast

Predicted with BIOWIN7

(Anaerobic Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Ready Biodegradability: YES

Ready Biodegradability Prediction

EPI Suite

(v.4.00) software

Hexadecane, C16H34(CAS No. 544-76-3)

 

QSARs

Biodegrades Fast

Predicted with BIOWIN1 (Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN2 (Non-Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Days -Weeks

Predicted with BIOWIN3 (Ultimate Biodegradation Timeframe)

EPI Suite

(v.4.00) software

QSARs

Days

Predicted with BIOWIN4 (Primary Biodegradation Timeframe)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN5 (MITI Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN6 (MITI Non-Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Does Not Biodegrade Fast

Predicted with BIOWIN7

(Anaerobic Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Ready Biodegradability: YES

Ready Biodegradability Prediction

EPI Suite

(v.4.00) software

Heptadecane, C17H36(CAS No. 629-78-7)

 

QSARs

Biodegrades Fast

Predicted with BIOWIN1 (Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN2 (Non-Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Days -Weeks

Predicted with BIOWIN3 (Ultimate Biodegradation Timeframe)

EPI Suite

(v.4.00) software

QSARs

Days

Predicted with BIOWIN4 (Primary Biodegradation Timeframe)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN5 (MITI Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN6 (MITI Non-Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Does Not Biodegrade Fast

Predicted with BIOWIN7

(Anaerobic Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Ready Biodegradability: YES

Ready Biodegradability Prediction

EPI Suite

(v.4.00) software

Octadecane, C18H38(CAS No. 593-45-3)

 

QSARs

Biodegrades Fast

Predicted with BIOWIN1 (Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN2 (Non-Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Weeks

Predicted with BIOWIN3 (Ultimate Biodegradation Timeframe)

EPI Suite

(v.4.00) software

QSARs

Days

Predicted with BIOWIN4 (Primary Biodegradation Timeframe)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN5 (MITI Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN6 (MITI Non-Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Does Not Biodegrade Fast

Predicted with BIOWIN7

(Anaerobic Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Ready Biodegradability: YES

Ready Biodegradability Prediction

EPI Suite

(v.4.00) software

Nonadecane, C19H40(CAS No. 629-92-5)

 

QSARs

Biodegrades Fast

Predicted with BIOWIN1 (Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN2 (Non-Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Weeks

Predicted with BIOWIN3 (Ultimate Biodegradation Timeframe)

EPI Suite

(v.4.00) software

QSARs

Days

Predicted with BIOWIN4 (Primary Biodegradation Timeframe)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN5 (MITI Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN6 (MITI Non-Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Does Not Biodegrade Fast

Predicted with BIOWIN7

(Anaerobic Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Ready Biodegradability: YES

Ready Biodegradability Prediction

EPI Suite

(v.4.00) software

Eicosane, C20H42(CAS No. 112-95-8)

 

QSARs

Biodegrades Fast

Predicted with BIOWIN1 (Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN2 (Non-Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Weeks

Predicted with BIOWIN3 (Ultimate Biodegradation Timeframe)

EPI Suite

(v.4.00) software

QSARs

Days

Predicted with BIOWIN4 (Primary Biodegradation Timeframe)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN5 (MITI Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN6 (MITI Non-Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN7

(Anaerobic Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Ready Biodegradability: YES

Ready Biodegradability Prediction

EPI Suite

(v.4.00) software

Henicosane, C21H44(CAS No. 629-94-7)

 

QSARs

Biodegrades Fast

Predicted with BIOWIN1 (Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN2 (Non-Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Weeks

Predicted with BIOWIN3 (Ultimate Biodegradation Timeframe)

EPI Suite

(v.4.00) software

QSARs

Days

Predicted with BIOWIN4 (Primary Biodegradation Timeframe)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN5 (MITI Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN6 (MITI Non-Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN7

(Anaerobic Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Ready Biodegradability: YES

Ready Biodegradability Prediction

EPI Suite

(v.4.00) software

Docosane, C22H46(CAS No. 629-97-0)

 

QSARs

Biodegrades Fast

Predicted with BIOWIN1 (Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN2 (Non-Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Weeks

Predicted with BIOWIN3 (Ultimate Biodegradation Timeframe)

EPI Suite

(v.4.00) software

QSARs

Days

Predicted with BIOWIN4 (Primary Biodegradation Timeframe)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN5 (MITI Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN6 (MITI Non-Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN7

(Anaerobic Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Ready Biodegradability: YES

Ready Biodegradability Prediction

EPI Suite

(v.4.00) software

Tricosane, C23H48(CAS No. 638-67-5)

 

QSARs

Biodegrades Fast

Predicted with BIOWIN1 (Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN2 (Non-Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Weeks

Predicted with BIOWIN3 (Ultimate Biodegradation Timeframe)

EPI Suite

(v.4.00) software

QSARs

Days

Predicted with BIOWIN4 (Primary Biodegradation Timeframe)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN5 (MITI Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN6 (MITI Non-Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN7

(Anaerobic Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Ready Biodegradability: YES

Ready Biodegradability Prediction

EPI Suite

(v.4.00) software

Tetracosane, C24H50 (CAS No. 646-31-1)

 

QSARs

Biodegrades Fast

Predicted with BIOWIN1 (Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN2 (Non-Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Weeks

Predicted with BIOWIN3 (Ultimate Biodegradation Timeframe)

EPI Suite

(v.4.00) software

QSARs

Days

Predicted with BIOWIN4 (Primary Biodegradation Timeframe)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN5 (MITI Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN6 (MITI Non-Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN7

(Anaerobic Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Ready Biodegradability: YES

Ready Biodegradability Prediction

EPI Suite

(v.4.00) software

Pentacosane, C25H52 (CAS No. 629-99-2)

 

QSARs

Biodegrades Fast

Predicted with BIOWIN1 (Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN2 (Non-Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Weeks

Predicted with BIOWIN3 (Ultimate Biodegradation Timeframe)

EPI Suite

(v.4.00) software

QSARs

Days

Predicted with BIOWIN4 (Primary Biodegradation Timeframe)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN5 (MITI Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN6 (MITI Non-Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN7

(Anaerobic Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Ready Biodegradability: YES

Ready Biodegradability Prediction

EPI Suite

(v.4.00) software

Hexacosane, C26H54 (CAS No 630-01-3)

 

QSARs

Biodegrades Fast

Predicted with BIOWIN1 (Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN2 (Non-Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Weeks

Predicted with BIOWIN3 (Ultimate Biodegradation Timeframe)

EPI Suite

(v.4.00) software

QSARs

Days

Predicted with BIOWIN4 (Primary Biodegradation Timeframe)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN5 (MITI Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN6 (MITI Non-Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN7

(Anaerobic Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Ready Biodegradability: YES

Ready Biodegradability Prediction

EPI Suite

(v.4.00) software

Heptacosane, C27H56 (CAS No. 593-49-7)

 

QSARs

Biodegrades Fast

Predicted with BIOWIN1 (Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN2 (Non-Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Weeks

Predicted with BIOWIN3 (Ultimate Biodegradation Timeframe)

EPI Suite

(v.4.00) software

QSARs

Days

Predicted with BIOWIN4 (Primary Biodegradation Timeframe)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN5 (MITI Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN6 (MITI Non-Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN7

(Anaerobic Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Ready Biodegradability: YES

Ready Biodegradability Prediction

EPI Suite

(v.4.00) software

Octacosane, C28H58 (CAS No. 630-02-4)

 

QSARs

Biodegrades Fast

Predicted with BIOWIN1 (Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN2 (Non-Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Weeks

Predicted with BIOWIN3 (Ultimate Biodegradation Timeframe)

EPI Suite

(v.4.00) software

QSARs

Days

Predicted with BIOWIN4 (Primary Biodegradation Timeframe)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN5 (MITI Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN6 (MITI Non-Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN7

(Anaerobic Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Ready Biodegradability: YES

Ready Biodegradability Prediction

EPI Suite

(v.4.00) software

Nonacosane, C29H60 (CAS No. 630-03-5)

 

QSARs

Biodegrades Fast

Predicted with BIOWIN1 (Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN2 (Non-Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Weeks

Predicted with BIOWIN3 (Ultimate Biodegradation Timeframe)

EPI Suite

(v.4.00) software

QSARs

Days

Predicted with BIOWIN4 (Primary Biodegradation Timeframe)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN5 (MITI Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN6 (MITI Non-Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN7

(Anaerobic Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Ready Biodegradability: YES

Ready Biodegradability Prediction

EPI Suite

(v.4.00) software

Triacontane, C30H62(CAS No. 638-68-6)

 

QSARs

Biodegrades Fast

Predicted with BIOWIN1 (Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN2 (Non-Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Weeks

Predicted with BIOWIN3 (Ultimate Biodegradation Timeframe)

EPI Suite

(v.4.00) software

QSARs

Days

Predicted with BIOWIN4 (Primary Biodegradation Timeframe)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN5 (MITI Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN6 (MITI Non-Linear Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Biodegrades Fast

Predicted with BIOWIN7

(Anaerobic Model Prediction)

EPI Suite

(v.4.00) software

QSARs

Ready Biodegradability: YES

Ready Biodegradability Prediction

EPI Suite

(v.4.00) software

Applicant's summary and conclusion

Conclusions:
The QSAR models predicts timeframe within days for primary biodegradation of most of Mineral Paraffin Oil components and days -weeks for their ultimate degradation.