Registration Dossier

Classification & Labelling & PBT assessment

DSD-DPD

General information

Name:
T003474
Status:
67/548/EEC self classification
Remarks:
T003474 is an intermediate in the synthesis of abiraterone acetate. T003474 is the last step before the API. Both compounds have a silimar structure. Therefore, read-across from the API abiraterone acetate is performed.

Classification

Explosiveness

Reason for no classification:
data lacking

Oxidising properties

Reason for no classification:
data lacking

Flammability

Reason for no classification:
data lacking

Thermal stability

Reason for no classification:
data lacking

Acute toxicity

Reason for no classification:
data lacking

Acute toxicity - irreversible damage after single exposure

Reason for no classification:
data lacking

Repeated dose toxicity

Classification:
Xn; R48/22 Harmful: danger of serious damage to health by prolonged exposure if swallowed.

Irritation / corrosion

Reason for no classification:
data lacking

Sensitisation

Reason for no classification:
data lacking

Carcinogenicity

Reason for no classification:
data lacking

Mutagenicity - genetic toxicity

Reason for no classification:
data lacking

Toxicity to reproduction - fertility

Classification:
Repr. Cat. 1; R60 May impair fertility.

Toxicity to reproduction - development

Classification:
Repr. Cat. 1; R61 May cause harm to the unborn child.

Toxicity to reproduction - breastfed babies

Reason for no classification:
data lacking

Environment

Reason for no classification:
data lacking

Labelling

Indication of danger

T - toxic

Risk phrases

R48/22 - Harmful: danger of serious damage to health by prolonged exposure if swallowed
R60 - May impair fertility
R61 - May cause harm to the unborn child

Specific concentration limits

Notes