1,4-Cyclohexanedicarboxylic acid, 1,4-bis[2-(2-ethoxyethoxy)ethyl] ester

Vapour pressure

Administrative data

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

28 March-27 June 2011

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: GLP compliant study according to guideline

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2011

Report date:

2011

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Version / remarks:

(2006)

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Version / remarks:

(OJEU no. L220, August 24, 2009)

Deviations:

no

Principles of method if other than guideline:

The isothermal thermogravimetric effusion method is validated in the range 10E-8 - 10E+3 Pa using a set of reference substances with known vapour pressures.

GLP compliance:

yes (incl. QA statement)

Type of method:

effusion method: by loss of weight or by trapping vaporisate

Test material

Test material information

Constituent 1

Reference substance name:

1,4-bis[2-(2-ethoxyethoxy)ethyl] cyclohexane-1,4-dicarboxylate

EC Number:

618-829-7

Cas Number:

922165-31-9

Molecular formula:

C20H36O8

IUPAC Name:

1,4-bis[2-(2-ethoxyethoxy)ethyl] cyclohexane-1,4-dicarboxylate

Details on test material:

Identification: Neosolue-Aqulio
Molecular formula: C20H36O8
Molecular weight: 404.5
CAS Number: 922165-31-9
Description: Clear colourless to very pale yellow liquid
Batch: TVI-714
Purity: 99.5% (GC)
Test substance storage: At room temperature in the dark
Stability under storage conditions: Stable
Expiry date: 07 October 2012 (Retest date)

Results and discussion

Vapour pressure

Temp.:

20 °C

Vapour pressure:

1.51 Pa

Remarks on result:

other: Equivalent to 1.13 x 10^-8 mm Hg

Any other information on results incl. tables

Results of the isothermal TGA analysis are shown in the table below. The coefficient of correlation (r) of the plot of the log v_Tof the test substance as function of the reciprocal temperatures was > 0.99. Extrapolation of the curve to 20°C resulted in a value of -8.79 for the logν_{T, 20}of the test substance. Fitting this value in the regression curve, a vapour pressure of 1.51 x 10 ^-6Pa = 1.13 x 10^-8mm Hg was obtained.

Temperature (°C)	Weight loss (µg/min)	νT (g/cm^2/h)	logνT
160	10.60	1.27´10^-3	- 2.90
	11.43	1.36´10^-3	- 2.87
170	21.31	2.54´10^-3	- 2.59
180	39.53	4.72´10^-3	- 2.33
	37.88	4.52´10^-3	- 2.34

 

Applicant's summary and conclusion

Conclusions:

The isothermal thermogravimetric effusion method was chosen for the determination of the vapour pressure of Neosolue-Aqulio. The vapour pressure of the test substance at 20°C (293K) was 1.51 x 10^-6 Pa = 1.13 x 10^-8 mm Hg.