Registration Dossier
Registration Dossier
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EC number: 907-658-6 | CAS number: -
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: A scientific review (peer reviewed). No data on GLP. The described method is not equivalent to OECD guideline.
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Unnamed
- Year:
- 1 975
Materials and methods
- Principles of method if other than guideline:
- Isobornyl acetate was applied full strengh to intact or abraded rabbit skin for 24 hours under occlusion.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Exo-1,7,7-trimethylbicyclo[2.2.1]hept-2-yl acetate
- EC Number:
- 204-727-6
- EC Name:
- Exo-1,7,7-trimethylbicyclo[2.2.1]hept-2-yl acetate
- Cas Number:
- 125-12-2
- Molecular formula:
- C12H20O2
- IUPAC Name:
- (1S,2S,4S) 1,7,7-trimethylbicyclo[2.2.1]hept-2-yl acetate
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- not specified
Test system
- Type of coverage:
- semiocclusive
- Preparation of test site:
- other: intact or abraded skin
- Vehicle:
- unchanged (no vehicle)
- Controls:
- not specified
- Duration of treatment / exposure:
- 24 h
Results and discussion
Any other information on results incl. tables
The substance has been described as mildly irritating to skin.
Applicant's summary and conclusion
- Interpretation of results:
- other: mildly irritating
- Conclusions:
- The substance was mildly irritating to skin.
- Executive summary:
The test of skin irritancy of isobornyl acetate was performed. The substance was applied full strength to intact or abraded rabbit skin for 24 hours under occlusion. Isobornyl acetate was mildly irritating to skin.
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