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Environmental fate & pathways

Biodegradation in water: screening tests

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Description of key information

Key study:- Clarke (2011a) 'CN-3384A: Assessment of ready biodegradability; CO2 evolution test' conducted in line with OECD Guideline 301B, EU Method C.4-C and EPA OPPTS 835.3110. The substance attained 0% degradation after 28 days and therefore cannot be considered to be readily biodegradable.
Supporting study:- Okubo (2011) ' Ready Biodegradability test of CN-3384A' conducted in line with Biodegradability Test of Chemical Substances by Microorganisms (Yakushokuhatsu 0331 No. 7, Heisei 23.03.29 Seikyoku No. 5, Kanpokihatsu No. 110331009, March 31, 2011. The study concluded that the substance was not readily biodegradable and no transformation products were generated under the conditions of the test, therefore supporting the results of the key study.

Key value for chemical safety assessment

Biodegradation in water:
under test conditions no biodegradation observed

Additional information

The key study was performed in compliance with GLP and to OCED Guideline 301B, EU Method C.4-C and EPA OPPTS 835.3110 with a sufficient level of detail to assess the quality of the study. The study was performed to a good standard in line with an accepted, standardised guideline and was assigned a reliability score of 1 using the criteria for assessing data quality as set out in Klimisch (1997).

The supporting study was performed in compliance with GLP and to Biodegradability Test of Chemical Substances by Microorganisms (Yakushokuhatsu 0331 No. 7, Heisei 23.03.29 Seikyoku No. 5, Kanpokihatsu No. 110331009, March 31, 2011 with a sufficient level of detail to assess the quality of the study. The study was performed to a good standard in line with an accepted, standardised Japanese guideline and was assigned a reliability score of 1 using the criteria for assessing data quality as set out in Klimisch (1997).