Registration Dossier

Administrative data

Endpoint:
skin sensitisation
Remarks:
other: not provided in study summary
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
other: Body responsible for the test
Title:
Unnamed
Year:
1988
Report Date:
1988

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: 84/449/EWG, B.6; OECD 406 (1981)(Meerscheweichen Maximeireungstest (GPMT))
GLP compliance:
yes
Type of study:
other: Meerscheweichen Maximeireungstest

Test material

Reference
Name:
Unnamed
Type:
Constituent

In vivo test system

Test animals

Species:
guinea pig
Strain:
Pirbright-Hartley

Study design: in vivo (non-LLNA)

Induction
Concentration / amount:
Concentration of test material and vehicle used at induction: ic: 2.5%
p.c.: 10%
Concentration of test material and vehicle used for each challenge: 5%
Challenge
Concentration / amount:
Concentration of test material and vehicle used at induction: ic: 2.5%
p.c.: 10%
Concentration of test material and vehicle used for each challenge: 5%
No. of animals per dose:
Number of animals in test group: 20
Number of animals in negative control group: 20

Results and discussion

Any other information on results incl. tables

Evidence of sensitisation of each challenge concentration: keine

Applicant's summary and conclusion

Interpretation of results:
other: not classified