Registration Dossier
Registration Dossier
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EC number: 231-441-9 | CAS number: 7550-45-0
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Original reference in foreign language
Data source
Reference
- Reference Type:
- publication
- Title:
- Toxicity of titanium tetrachloride
- Author:
- Yang H; Zhang J, Feng S, Wang X, Chen Y, Liu Y
- Year:
- 1 997
- Bibliographic source:
- Weisheng Dulixue Zazhi 11(2): 131-133
Materials and methods
- Principles of method if other than guideline:
- Rats were exposed to the test substance, an oral LD50 value was determined
- GLP compliance:
- not specified
- Test type:
- standard acute method
Test material
- Reference substance name:
- Titanium tetrachloride
- EC Number:
- 231-441-9
- EC Name:
- Titanium tetrachloride
- Cas Number:
- 7550-45-0
- Molecular formula:
- Cl4Ti
- IUPAC Name:
- titanium tetrachloride
- Details on test material:
- unknown
Constituent 1
Test animals
- Species:
- rat
- Strain:
- other: unknown
- Sex:
- male/female
- Details on test animals or test system and environmental conditions:
- TEST ANIMALS
- Weight at study initiation: 180-220 g
ENVIRONMENTAL CONDITIONS
unknown
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- other: unknown
- Details on oral exposure:
- unknown
- Doses:
- unknown
- No. of animals per sex per dose:
- unknown
- Control animals:
- other: unknown
- Details on study design:
- unknown
- Statistics:
- unknown
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- 586.76 mg/kg bw
- 95% CL:
- >= 510.15 - <= 678.87
- Mortality:
- unknown
- Clinical signs:
- unknown
- Body weight:
- unknown
- Gross pathology:
- unknown
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
