Registration Dossier
Registration Dossier
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EC number: 911-351-2 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Additional information
One reliable key study is available to assess the hydrolysis potential of the registered reaction mass. This study was performed according to Method C7 Abiotic Degradation, Hydrolysis as a Function of pH and Method 111 of the OECD Guidelines for Testing of Chemicals, with GLP statement. The measured hydrolytic half-lives at 25 °C of the two main components of the reaction mass (monoester and diester components) are greater than 1 year at any of the pH tested (4.0, 7.0 and 9.0). This study is supported by an analytical method validation to confirm the linear response for the HPLC-MS analytical method using standard solutions prepared in the same matrix (acetonitrile: water: acetic acid (50:45:5 v/v/v)). This study was performed according to scientifically sounds method and under GLP. In all matrices investigated, representative of those used during the hydrolysis study, both the monoester and diester components were confirmed to demonstrate first order correlation coefficient values of greater than or equal to 0.999 over a nominal concentration range (0 to 85 mg/L) incorporating those analyzed under the hydrolysis study.
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