Registration Dossier
Registration Dossier
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EC number: 235-120-4 | CAS number: 12070-08-5
Endpoint summary
Administrative data
Key value for chemical safety assessment
Genetic toxicity in vitro
Description of key information
The results from a transformation/dissolution test (Rodriguez et al., 2012, see IUCLID section 4.8) showed that the test substance titanium carbide is practically not soluble in water or pH neutral media. It will therefore not be possible to obtain a solution of the test material in cell culture medium in order to perform in vitro genetic toxicity testing.
Link to relevant study records
- Endpoint:
- in vitro gene mutation study in bacteria
- Data waiving:
- study technically not feasible
- Justification for data waiving:
- other:
- Endpoint:
- in vitro cytogenicity / chromosome aberration study in mammalian cells
- Data waiving:
- study technically not feasible
- Justification for data waiving:
- other:
- Endpoint:
- in vitro gene mutation study in mammalian cells
- Data waiving:
- study technically not feasible
- Justification for data waiving:
- other:
Referenceopen allclose all
Endpoint conclusion
- Endpoint conclusion:
- no study available
Genetic toxicity in vivo
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Justification for classification or non-classification
The results from a transformation/dissolution test (Rodriguez et al., 2012, see IUCLID section 4.8) showed that the test substance titanium carbide is practically not soluble in water or pH neutral media. It will therefore not be possible to obtain a solution of the test material in cell culture medium in order to perform in vitro genetic toxicity testing.
Based on this information, no classification for mutagenicity according to Regulation (EC) 1272/2008 is warranted for the test substance.
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