Registration Dossier

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

48h EC50 (Daphnia magna) >= 5.5 mg/L (freshwater, nominal concentration)
48h LC50 (Artemia salina) >= 3.15 mg/L (marine water, nominal concentration)

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
5.5 mg/L

Marine water invertebrates

Marine water invertebrates
Effect concentration:
3.15 mg/L

Additional information

Since no reliable short-term test involving aquatic invertebrates is available for C10-12AS Na (CAS 85049-86-1), in accordance to Regulation (EC) 1907/2006 Annex XI, 1.5, a read-across to other structurally related category members was conducted. Read-across data from C10AS Na (CAS 142-87-0) and C12AS Na (CAS 151-21-3) were used, since toxicity of alkyl sulfates is dependent on carbon chain length.

Two short-term studies with aquatic invertebrates are available for C12AS Na (CAS 151-21-3). In a key, non-GLP test Ceriodaphnia dubia was exposed to six test concentrations of C12AS Na (CAS 151-21-3) up to 101 mg/L (Lauth 1996). The test was performed under flow-through conditions, no special guideline was followed. Mortality of daphnids was evaluated daily; the EC50 value determined after 48 hours of exposure was 5.55 mg/L. Furthermore, a non-GLP study with CAS 151-21-3 using a common marine species (Artemia salina) is available. In this static test mortality of Artemia was determined in culture dishes using six concentrations of test substance up to 18 mg/L (nominal concentrations). The LC50 value after 48 hours of exposure ranged between 3.15 and 3.8 mg/L (nominal concentration).

Moreover, two 24-hour tests with Daphnia magna are available for C10AS Na (CAS 142-87-0). The first non-GLP study was performed following an AFNOR T.90301 (1974) method (Lundahl and Cabridenc 1978). The obtained results showed that the 24-hour EC50 value was 800 mg/L (nominal concentrations). Analytical measurements are not available. The other non-GLP study with Daphnia magna followed a method described by Norme Francaise Homologue, 1983, NF T90-31 (Sanchez Leal 1991). The 24-hour EC50 value was 470 mg/L. Analytical check of the test concentrations was not provided.

Due to structural and property similarities with the tested category member, it can be concluded that the above result applies also to C10-12AS Na (CAS 85049-86-1). As the toxicity of alkyl sulfates is dependent on the carbon chain length, it is expected that the toxic effects of C10-12AS Na (CAS 85049-86-1) will be lower than of the pure C12 homologue, but on the other hand slightly higher than C10 homologue. The 48-hour EC50 value to the aquatic invertebrates will be equal or higher than 5.5 mg/L for freshwater invertebrates and equal or higher than 3.15 mg/L for marine invertebrates.