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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information


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Administrative data

Description of key information

The toxicology of ITC 288/S has been investigated in oral study (OECD 407, Kr:1), leading to the conclusion that this substance is of very low  toxicity, NOAEL ≥ 1000 mg/kg bw/day, any systemic toxicity was reported (test proposal for 90 days/oral was made). The genotoxic potential of ITC 288/S has been investigated both in vitro and in vivo. ITC 288/S is considered as not genotoxic.
Although no chronic carcinogenicity study has been performed, the available data indicate that ITC 288/S does not present a carcinogenic hazard.

Key value for chemical safety assessment

Justification for classification or non-classification

Additional information