Registration Dossier
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EC number: 271-689-5 | CAS number: 68604-38-6
Toxicity to terrestrial arthropods
Administrative data
Link to relevant study record(s)
Description of key information
The chemical safety assessment according to Annex I of Regulation (EC) No. 1907/2006 does not indicate the need to investigate further the toxicity to terrestrial arthropods.
Key value for chemical safety assessment
Additional information
Experimental data on the toxicity of Fatty acids, C16-18 and
C18-unsatd., hexaesters with dipentaerythritol (CAS 68604-38-6) to
terrestrial arthropods are not available. In accordance with Regulation
(EC) No. 1907/2006, Annex IX, column 2, 9.4 studies on terrestrial
organisms do not need to be conducted when there is no risk indicated by
the chemical safety assessment.
Based on the available experimental toxicity data the substance is
expected to be not toxic to soil organisms. The substance is expected to
be largely physically removed in sewage treatment plants and thus a
transfer to the terrestrial environment is not likely (according to the
Guidance on information requirements and chemical safety assessment,
Chapter R.7b (ECHA, 2012)). If transferred to the soil an adsorption to
soil particles is probable as indicated by the high log Koc (C16 FA
component: 2.27, C18 unsat. FA component: 46.87, C18 FA component:
48.16; KOWWIN v1.68; Blum, 2011). Therefore the substance might be
ingested by soil-dwelling organism feeding on soil particles. When
ingested by soil dwelling organisms, the substance is expected to be
metabolised and thus an accumulation and/or chronic effects are not
likely. The lack of chronic toxicity was demonstrated by a chronic
toxicity test on Eisenia fetida (OECD 222). Neither mortality nor an
effect on earthworm reproduction was observed (NOEC
reproduction/mortality: 1000 mg/kg soil dw).
Moreover, a chronic toxicity test with aquatic invertebrates is
conducted with Fatty acids, C16-18 and C18-unsatd., hexaesters with
dipentaerythritol (CAS 68604-38-6). The substance did not show any
chronic effects up to the highest tested concentration of 100 mg/L on
the water flea Daphnia magna in a GLP study according to OECD 211.
In accordance with Regulation (EC) No. 1907/2006, Annex X, Column 2, 9.4
further studies on the effects on terrestrial organisms do not have to
be conducted since the chemical safety assessment indicates that
toxicity to terrestrial arthropods is not expected to be of concern.
A detailed reference list is provided in the technical dossier (see IUCLID, section 13) and within CSR.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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