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Ecotoxicological information

Toxicity to microorganisms

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Description of key information

NOEC (14 d) ≥ 20 mg/L (Toxicity control of ready biodegradation test OECD 301B)

Key value for chemical safety assessment

Additional information

Studies on the toxicity of Fatty acids, C16-18 and C18-unsatd., hexaesters with dipentaerythritol (CAS 68604-38-6) to aquatic microorganisms are not available. Therefore the assessment of the toxicity to microorganisms is based on the NOEC determined in the toxicity control reported in the study on ready biodegradability. This approach is suitable for substances with high degrading rates or no degradation inhibition in the positive control in ready biodegradability tests. This is in accordance with the Guidance on information requirements and chemical safety assessment (Chapter R.7b: Endpoint specific guidance, ECHA 2012).
A substance can be assumed to be not inhibitory to aquatic microorganisms, if in the toxicity control of a ready biodegradation test, more than 25% degradation based on CO2 evolution occurred within 14 days (OECD guideline 301). For Fatty acids, C16-18 and C18-unsatd., hexaesters with dipentaerythritol (CAS 68604-38-6) a biodegradation test according to OECD guideline 301B is available (Caduff, 2012). The test includes a toxicity control, which contains 20 mg/L of the test substance and 20 mg/L of the reference material (sodium benzoate). The toxicity control attained 26.7% degradation after 5 days of incubation (40.9% after 14 d). Hence, the substance is not toxic to aquatic microorganisms in the toxicity control and the test item concentration of 20 mg/L can be used as NOEC (14 d).

A detailed reference list is provided in the technical dossier (see IUCLID, section 13) and within CSR.