Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 201-919-1 | CAS number: 89-57-6
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- migrated information: read-across based on grouping of substances (category approach)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Referenceopen allclose all
- Title:
- No information
- Author:
- Anonymous
- Year:
- 2 016
- Bibliographic source:
- OECD Toolbox v3.3
- Title:
- No information
- Author:
- Anonymous
- Year:
- 2 011
- Bibliographic source:
- Sigma Aldrich safety data sheet
Materials and methods
Test guideline
- Guideline:
- other: read across
- GLP compliance:
- no
Test material
- Reference substance name:
- 5-aminosalicylic acid
- EC Number:
- 201-919-1
- EC Name:
- 5-aminosalicylic acid
- Cas Number:
- 89-57-6
- Molecular formula:
- C7H7NO3
- IUPAC Name:
- 5-amino-2-hydroxybenzoic acid
Constituent 1
Results and discussion
In vivo
Results
- Irritation parameter:
- primary dermal irritation index (PDII)
- Basis:
- mean
- Score:
- 1.4
- Max. score:
- 8
Any other information on results incl. tables
See attached OECD Toolbox study for skin irritation/corrosion
Applicant's summary and conclusion
- Interpretation of results:
- irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- Classification Xi;R38 (DSD) respectively Skin irritant catecory 2 with H315 (CLP)
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
