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Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Link to relevant study record(s)

Description of key information

Long-term effects on aquatic invertebrates are not to be expected.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Dose descriptor:
Effect concentration:
>= 11.6 mg/L

Additional information

The long-term toxicity of the substance to aquatic invertebrates was tested in a GLP guideline study according to OECD 211 using Daphnia magna as test species (BASF SE, 2021; report no. 51E0091/20E007). The daphnids were exposed under semi-static conditions to investigate effects on their reproduction. The test concentrations were analytically verified and proved to be stable. No significant mortality, reduced reproduction or any other additional significant adverse effects or abnormal behavior were observed in any of the test treatments. Therefore, the 21-d NOEC was determined to be  >= 11.6 mg/L (meas.; >= 10.9 mg/L, nominal).


This result is supported by a study with C. dubia following the French guideline AFNOR NF T 90-376 (2000) (Devillers et al., 2003). The test concentrations were not analytically controlled; however, it can beassumed that they were stable based on the results of the recent studies with analytical monitoring by BASF SE. The 7-d EC10 was determined to be 19.6 mg/L.


It can be concluded that long-term effects on aquatic invertebrates are not to be expected.