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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Link to relevant study record(s)

Description of key information

Data waiving: Based on the ready biodegradability study the test substance is not toxic to microorganisms.

Absence of microbial toxicity can be inferred from biodegradation studies in the laboratory. The information content of ready biodegradability tests can be used to derive a NOEC. The assumption that the substance under investigation is not inhibitory to the micro-organisms when dosed in the test system is implicit in ready biodegradability testing. If a compound does not inhibit the degradation of a positive control at a certain concentration, this concentration can be used as a NOEC value.

Any Ready Biodegradability Test relying on continuous monitoring or the Manometric Respirometry test (OECD 301F) is considered more reliable for observing the effects of a chemical on the inoculum.

Based on the ready biodegradability study the test substance is not toxic to microorganisms since it does not inhibit the degradation of a positive control at 100 mg/L. Therefore, this concentration can be used as a NOEC value.

Key value for chemical safety assessment

EC10 or NOEC for microorganisms:
100 mg/L

Additional information