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Short-term toxicity to aquatic invertebrates

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Description of key information

48 h EC50: 52 mg/L

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
52 mg/L

Additional information

In the Klimisch 1 GLP study from Kimmel (2013) the acute toxicity of Aspartic acid, N-(3-carboxy-1-oxo-sulfopropyl)-N-(C16-C18 (even numbered), C18unsaturated alkyl) tetrasodium salts on Daphnia magna was determined in an 48 hour static test according to OECD 202 and EU method C.2. The test was performed with concentrations of 6.25, 12.5, 25, 50 and 100 mg active substance/L and a blank control. Four replicates with 5 daphnids each were set up. After 48 hours 0, 0, 0. 0, 65 and 100 % immobilization was observed in the control and at test concentrations of 6.25, 12.5, 25, 50 and 100 mg active substance/L, respectively. Analytical measurements confirmed that the test solutions were correctly dosed and stable throughout the exposure period. Therefore the data were evaluated based on nominal concentrations. The EC50 is 52 mg as/L, the NOEC is 25 mg as/L.

The results are considered relevant and reliable for the risk assessment.