Registration Dossier
Registration Dossier
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EC number: 410-860-2 | CAS number: 79815-20-6 [S]-2-INDOLINE CARBOXYLIC ACID
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Adequacy of study:
- other information
Data source
Reference
- Reference Type:
- other: Body responsible for the test
- Title:
- Unnamed
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 402 (Acute Dermal Toxicity)
- GLP compliance:
- yes
- Limit test:
- yes
Test animals
- Species:
- other: Rat, spraque-dawley
Administration / exposure
- Type of coverage:
- occlusive
- Vehicle:
- other: distilled water
- Duration of exposure:
- 24 h
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
Any other information on results incl. tables
Mortality
Male: 2000 mg/kg bw; Number of animals: 5; Number of deaths: 0
Female: 2000 mg/kg bw; Number of animals: 5; Number of deaths: 0
Clinical signs
Signs of toxicity related to dose levels:
Bodyweight hains were recorded for all rats on days 8 and 15.
Gross pathology
Effect on organs:
No treatment related effetcts were observed.
Other findings
Signs of toxicity (local):
No treatment related effects were observed.
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
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