Registration Dossier
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EC number: 223-829-1 | CAS number: 4090-51-1
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
In a reliable (reliability category 1) acute toxicity test performed compliant to GLP with analytical monitoring of submission substance concentration no signs of toxicity to Daphnia magna were observed at the nominal limit concentration of 77 mg submission substance/L (saturated solution). Thus no EC50 could be determined.
Key value for chemical safety assessment
Additional information
Acute toxicity of the submission substance towards aquatic invertebrates was assessed by means of a limit test performed compliant to GLP in accordance with Commission Directive 92/69/EEC (1992) and OECD 202 (1984) (reliability category 1). Due to the very poor solubility of the submission substance in water, the mean measured concentrations in test medium at the nominal limit concentration of 77 mg/L submission substance after filtration through a Whatman GF/C-Filter with a pore size of approximately 1.2 µm were 53 µg/L at test start and 51 µg/L after 48 hours (saturated solution). The test material was spread over the water surface and the bottom of the glass-beakers. Neither in the control nor at the nominal limit concentration of 77 mg/L submission substance any immobilized or dead daphnids were observed till the end of the test. Therefore, the 48-hour NOEC (highest concentration tested without toxic effects after the exposure period of 48 hours), and the 48-hour EC0 of the submission substance to Daphnia magna were determined to be at least 77 mg submission substance/L.
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