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EC number: 939-607-9
CAS number: 1474044-65-9
In a guideline study, the 28 day NOEC of C12-16 ABDAC for hatchability of Fathead minnow eggs was 0.273 mg a.i./L. The 28 day NOEC for survival was 0.0322 mg a.i./L and the 28 day NOEC for growth was > 0.0322 mg a.i./L).
A guideline study
was conducted to determine the effect ofthe
read-across substance C12-16 ADBAC on
toxicity, mortality, hatchability and growth of Fathead minnow (Pimephales
promelas). Fathead minnow eggs (80 per concentration) were exposed
to mean measured concentrations of 0, 32.3, 75.9, 134.2, 186.8, 273.2
and 488.7 mg a.i./L of the radiolabelled test substance. Analytical
determination was performed and the sample concentrations were verified
by liquid scintillation counting. After 7 days, surviving fry from two
replicates were thinned to 10 animals per replicate for each exposure
group (total of 20 animals per concentration) and exposed to the same
concentrations for a 28 day post-hatch static renewal toxicity test.
Observations of symptoms and mortality were conducted daily. Under the
conditions of the study, the 28 day NOEC for hatchability was 0.274
mg/L, the 28 day NOEC for survival was 0.0322 mg a.i./L and the 28 day
NOEC for growth was > 0.0322 mg a.i./L) (McIntyre DO and Pate HO, 1992).
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