Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: secondary source

Data source

Referenceopen allclose all

Title:
No information
Author:
Cancer Res, vol 39, 2204 (1979) (citation RTECS)
Title:
No information
Author:
RTECS Number NR0200000 (1994)

Materials and methods

Principles of method if other than guideline:
intraperitoneal application of the test substance on mice
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
α,α,α-trifluoro-3-tolyl isocyanate
EC Number:
206-341-3
EC Name:
α,α,α-trifluoro-3-tolyl isocyanate
Cas Number:
329-01-1
Molecular formula:
C8H4F3NO
IUPAC Name:
1-isocyanato-3-(trifluoromethyl)benzene
Constituent 2
Reference substance name:
alpha,alpha,alpha-trifluoro-3-tolyl isocyanate
IUPAC Name:
alpha,alpha,alpha-trifluoro-3-tolyl isocyanate
Details on test material:
Test substance: no data

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
not specified
Doses:
no data
No. of animals per sex per dose:
no data
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
871 mg/kg bw

Any other information on results incl. tables

no data

Applicant's summary and conclusion

Executive summary:

LD50 (i.p.) = 871 mg/kg bw (mouse)