Registration Dossier

Physical & Chemical properties

Partition coefficient

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Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2003
Report Date:
2003

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.8 (Partition Coefficient)
Deviations:
no
Principles of method if other than guideline:
Since the test substance is a salt, both the Flask-shaking method and the HPLC method are not applicable. Therefore, the Estimation method was used for the determination of the partition coefficient of MMC.
GLP compliance:
yes
Type of method:
other: Estimation method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
-1.17
Remarks on result:
other: calculated as a quotient of the n-octanol solubility and the water solubility of MMC

Applicant's summary and conclusion

Conclusions:
The partition coefficient (n-octanol/water), Pow, calculated as a quotient of the n-octanol solubility and the water solubility of MMC, is 0.068
(log P ow -1.17).