Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
dermal absorption
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Data from database
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
secondary source
Title:
Unnamed
Year:
2012
Report date:
2012

Materials and methods

Test guideline
Guideline:
other: REACH guidance on QSARs R.6, May/July 2008
Principles of method if other than guideline:
Danish (Q)SAR database report

Test material

Constituent 1
Reference substance name:
649747-80-8
Cas Number:
649747-80-8
IUPAC Name:
649747-80-8
Details on test material:
- Name of test material (as cited in study report): Fatty acids, C8-10, 2-ethylhexyl esters
- Analytical purity: no data

Results and discussion

Absorption in different matrices:
Dermal absorption of Fatty acids, C8-10, 2-ethylhexyl esters was predicted to be in the range of 1.69E-06 to 4.63E-06 mg/cm²/event (very low).

Applicant's summary and conclusion