Registration Dossier
Registration Dossier
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EC number: 233-790-2 | CAS number: 10361-43-0
Toxicity to birds
Administrative data
Link to relevant study record(s)
Description of key information
In one dietary toxicity study with Leghorn hens, NOEC values of ≥1000 mg Bi/kg diet were reported for egg production,
Key value for chemical safety assessment
- Long-term EC10, LC10 or NOEC for birds:
- 1 000 mg/kg food
Additional information
Only one dietary toxicity study with Leghorn hens was identified, reporting NOEC values of ≥1000 mg bismuth/kg diet for egg production, individual feed intake and body weight change after 8 weeks feeding with a corn-soy laying mash supplemented with read-across substance, dibismuth trioxide (Hermayer et al., 1977). This study was judged not assignable (Klimisch 4) because of the lack of information on both methods and results. However, the results were used in a weight-of-evidence approach indicating the limited risk for chronic dietary toxicity of bismuth metal and bismuth compounds.
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