Registration Dossier

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

The test substance was tested in an OECD screening test (OECD 301 D). After 28 d no biodegradation (-3%) was observed, whereas after a test prolongation up to 60days a slight biodegradation activity of 10-20 % was observed. It is concluded that the test item is neither readily biodegradable nor inherently biodegradable under the chosen conditions.

In the Guidance on Information requirements and chemical safety assessment R11 PBT, additional assessment criteria are indicated whether a substance may potentially fulfil criteria for PBT. The two recommended models Biowin 2 (non linear model prediction) and Biowin 3 (ultimate biodegradation time) within the complete Biowin-family (Biowin1-6) have been used to screen the test item for criteria of persistence.

 

Additional modeling using Biowin 1-6 by Biowin vs. 4.10 was performed with the test item to screen if the substance potentially fulfils criteria for PBT. In all 6 models the criteria for fast or readily (bio)degradation were met. Special care was taken to the results of Biowin 2&3, but again the borderline values for the criteria P were by far exceeded, Biowin2 =0.94 and Biowin 3 = 3.2. Based on the screening models there is no indication that the test item is persistent.

Although, the QSAR modelling may indicate that the substance is not persistent, the registrant decides on the current stage of knowledge to evaluate the substance based on the prolonged screening test to be not biodegradable.

Additional information