Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to soil macroorganisms except arthropods

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

 EC50 > 1000 mg/kg soil dw, LC50 > 1000 mg/kg soil dw, LOEC > 1000 mg/kg soil dw, NOEC 1000 mg/kg soil dw (reported as mg ai/kg soil, active ingredient, values were corrected for sample purity), OECD 207,Malorin & Kranzfelder 1999.

Key value for chemical safety assessment

Long-term EC10, LC10 or NOEC for soil macroorganisms:
1 000 mg/kg soil dw

Additional information

The toxicity to soil macroorganisms was determined in an acute earthworm toxicity study where Eisenia foetida were exposed to the test material at the following nominal concentrations; 62.5, 125, 250, 500 and 1000 mg/kg. Controls and the reference substance (2-chloroacetamide) were run concurrently for comparison. Under the conditions of the test the observed rate of mortality ranged from 0 to 5 % in exposure groups, where the control was 0 %. As the rate of mortality was < 50 % it can be said that the LC₅₀ > 1000 mg/kg. Weight change ranged from -7 % to 2 % in exposure groups where the mean control was -0.5 %. Weight change showed no statistical significance and the EC₅₀ was determined to be > 1000 mg/kg. No systemic signs of toxicity were recorded throughout the study and the test material was shown to be non-toxic to earthworms. The NOEC was determined to be 1000 mg/kg and the LOEC > 1000 mg/kg, based on the observations from both mortality and weight change data. The LC₅₀ determined for the reference substance was within the specific laboratories historical range.

The study was performed according to GLP, in line with standardised guidelines, with a high standard of reporting and has thus been assigned a reliability score of 1 in line with the principles for assessing data quality set out by Klimisch (1997). The study is considered to be reliable, relevant and adequate for risk assessment purposes.

The available data are considered to be complete and the following conclusions for toxicity have been taken forward for risk assessment; NOEC 1000 mg/kg soil and EC₅₀ or LC₅₀ > 1000 mg/kg soil (reported as mg ai/kg soil, active ingredient, values were corrected for sample purity).