2-Pyridinesulfonamide, N-[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]-3-(2,2,2-trifluoroethoxy)-, sodium salt (1:1)

Explosiveness

Description of key information

Non explosive,  EU Method A.14,  Angly 2000

Key value for chemical safety assessment

Explosiveness:

non explosive

Additional information

The explosivity of the test material was determined in three tests performed in accordance with the standardised guideline EU Method A.14. The explosivity of the test material was assessed using mechanical sensitivity (shock), mechanical sensitivity (friction) and thermal sensitivity tests. All tests provided negative results in the early stages of testing and so were not extended for further assessment. Under the conditions of the three tests, the test material was considered to be non-explosive.

The study was performed in line with GLP and an accepted standardised guideline with a high standard of reporting. The study was assigned a reliability score of 1 in accordance with the principles of assessing data quality outlined in Klimisch (1997) and considered suitable for assessment as an accurate reflection of the test material.

The test methods required for assessment under Regulation (EC) No. 1272/2008 (UN Recommendation on Transport of Dangerous Goods) differ slightly from those described in Regulation (EC) No. 440/2008. Tests A.14 and E.1 differ in that the latter is tested to a smaller limiting diameter (respectively 2mm vs 1mm), and hence is a more sensitive test. As such, the available data is adequate for classification purposes under Directive 67/548/EEC, but is not adequate for the requirements of Regulation (EC) No. 1272/2008.

Inspection of the molecular structure of the substance did not identify any functional groups identified in the UN Recommendations on the Transport of Dangerous Goods, Manual of Tests and Criteria, Appendix 6, Table A6.1, as being associated with explosive properties. As a result, and in combination with the above test results, further testing is not considered to be necessary.

The available data are considered to be complete and the conclusion, non-explosive, was taken forward for risk assessment.

Justification for classification or non-classification

In accordance with Regulation EC No. 1272/2008, the test material does not require classification as explosive as it produced negative results in the early stages of all the explosive tests performed and assessment of the structure of the test material did not indicate and groups present on the molecule associated with explosivity in accordance with the provisions described in the UN Recommendations on the Transport of Dangerous Goods, Manual of Tests and Criteria, Appendix 6, Table A6.1. 

In accordance with Directive 2001/59/EC, the test material does not require classification as explosive as it produced negative results in the early stages of all the explosive tests performed and assessment of the structure of the test material did not indicate and groups present on the molecule associated with explosivity.