Registration Dossier
Registration Dossier
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EC number: 203-537-0 | CAS number: 107-96-0
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Insufficient data to determine reliability
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Unpublished data Eastman Kodak.
- Author:
- Fassett, D.W.
- Year:
- 1 963
- Bibliographic source:
- Summarized in Patty's Industrial Hygiene and Toxicology |2nd Ed. Interscience Publishers, New York, New York.
Materials and methods
- GLP compliance:
- no
Test material
- Reference substance name:
- 3-mercaptopropionic acid
- EC Number:
- 203-537-0
- EC Name:
- 3-mercaptopropionic acid
- Cas Number:
- 107-96-0
- Molecular formula:
- C3H6O2S
- IUPAC Name:
- 3-sulfanylpropanoic acid
- Details on test material:
- IUCLID4 Test substance: as prescribed by 1.1 - 1.4
Constituent 1
Test animals
- Species:
- guinea pig
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Vehicle:
- water
Results and discussion
Any other information on results incl. tables
RS-Freetext:
Neat material appears to be absorbed directly through the
guinea pig skin with deaths from as low as 5 ml/kg. Severe
delayed eschar formation was noted.
A 10% solution in water applied as a compress to guinea pig
skin produces severe damage and eschar. No deaths were
produced at this concentration.
No additional information provided.
Applicant's summary and conclusion
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