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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Description of key information

72 h ErC10: 10 mg/L
72 h ErC50: 46 mg/L

Key value for chemical safety assessment

EC50 for freshwater algae:
46 mg/L
EC10 or NOEC for freshwater algae:
10 mg/L

Additional information

In the Klimisch 1 GLP study from Kimmel (2013) the toxicity of Butanedioic acid, sulfo-, 4-C12-14-alkyl esters, disodium salts toDesmodesmus subspicatuswas determined in a static 72-Hour Algal Growth Inhibition Test. The test was performed according to OECD 201 and EU Method C.3. The nominal test concentrations were 0 (control), 6.25, 12.5, 25, 50 and 100 mg test item/L. Six control replicates and 3 replicates from each test solution were set up. Dose verification analysis was performed and confirmed the correct dosage and stability of the test item throughout the test period. In order to determine the growth of the cultures, the cells were counted using a coulter counter. The cell density was determined at 0, 24, 48 and 72 hours. The growth of the control cultures fulfilled the validity criteria from OECD 201 (2006). The 72 -hour ErC10 and ErC50 are 10 and 46 mg test item/L based on the nominal concentration.

This information is considered to be relevant and reliable for the further risk assessment.