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EC number: 209-151-9 | CAS number: 557-05-1
Group/ Dose (mg/kg)
Body Weight (gram)
Body Weight Change (%)
Rats Body Weight (g)
Body Weight Changes (%)
Keys:SD = Standard Deviation, n = Number of Animals
Hours (Day 0)
Acute oral toxicity study of test chemical performed on Rats as per OECD No. 423. Six female Wistar rats were selected for acute oral toxcity. Rats were fasted for 16 to 18 hours, prior to dosing (water was given ad libitum). After test item administration, feed was withheld for a further 4 hours. The time interval between dosing was determined by the onset, duration and severity of toxic signs Three rats of group G1 were dosed with starting dose of 2000 mg/kg body weight and the animals showed no mortality post dosing, so another three rats of the same group were dosed with 2000 mg/kg weight and no mortality was observed. At 2000mg/kg, all the six animals were observed with normal clinical sign till day 14 . No mortality was observed througout the experimentation period. Mean body weight of animals treated with 2000mg/kg body weight was observed with gain on day 7 and 14, as compared to day 0 .No external and internal gross pathological examination were seen in all the six animals treated with 2000 mg/kg body weight during terminal sacrifice Under the conditions of this; acute oral toxicity study of test chemical in female rats is as given below: The acute oral LD50 value of test chemical was >2000 mg/kg body weight. Thus by considering the CLP criteria for acute toxicity rating for the chemicals, it infers that test chemical does not exhibit acute oral toxicity i.e it is acutely non toxic to animals
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