3-acetoxymethylen-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Flammability

Administrative data

Endpoint:

flammable solids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

October 2009

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Comparable to guideline study (EC A.10.) with acceptable restrictions

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2009

Report date:

2009

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

EU Method A.10 (Flammability (Solids))

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

other: UN Transport Regulation Test N.1

Deviations:

no

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

3-acetoxymethylen-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

EC Number:

213-485-0

EC Name:

3-acetoxymethylen-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Cas Number:

957-68-6

Molecular formula:

C10H12N2O5S

IUPAC Name:

(6R,7R)-3-[(acetyloxy)methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Test material form:

solid: particulate/powder

Remarks:

migrated information: powder

Details on test material:

Name: 7-Aminocefalosporansäure (7-ACA)
Lot no.: 34212818

Results and discussion

Flammable solids

Test procedure:

burning time (test type not further specified)

Remarks:

or specified in description of method (migrated information)

Burning time:

>= 3 490 s

Applicant's summary and conclusion

Interpretation of results:

non flammable

Remarks:

Migrated information

Conclusions:

The combustion time of the test item over a distance of 200 mm was 3490 s.
The product has to be classified neither as highly flammable solid according to EC 440/2008, Part A, A.10., nor as readily combustible solid in class 4.1 according to the UN-Transport Regulation and nor as flammable solid according to GHS.

Executive summary:

The determination of the burning number of a powdery substance was performed according to the guideline VDI 2263, sheet 1. The burning number can vary between BZ 1 and BZ 6.

For the determination of the burning number, the sample is placed on a ceramical plate in the shape of a line being 4 cm long and 2 cm wide at room temperature or alternatively at 100 °C. An ignition source (flame or glowing coil) is applied to the pile and the burning number between BZ 1 and BZ 6 determined. In case the sample melts and can thus not burn, it is blended with 20 wt.-% Kieselgur the burning number is determined again.

For the preliminary test according to EC 440/2008, the test item is prepared as explained above. As ignition source, a flame is applied on the test item until it ignites or for at least 2 minutes (for metal dusts and metal alloys 5 minutes). The main test has to be performed in case the test item burns over a distance of 200 mm within 4 minutes (40 minutes for metal dusts). Otherwise, the test item is not classified as highly flammable solid according to EC 440/2008, Annex V, Part A, A.10..

For the preliminary test according to the UN-Transport Regulations and to GHS (CLP-Guideline) the test is performed as described above. The main test has to be performed in case the test item burns over a distance of 200 mm within 2 minutes (20 minutes for metal dusts). Otherwise, the test item is not classified as readily combustible solid of Class 4 Division 4.1 of the UN Transportation regulations and as flammable solid according to GHS, respectively.