Registration Dossier
Registration Dossier
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EC number: 272-574-2 | CAS number: 68890-66-4
Carcinogenicity
Administrative data
Description of key information
Key value for chemical safety assessment
Justification for classification or non-classification
Since Octopirox has no genotoxic properties, is not mutagenic, and there are no indications for the induction of hyperplasia and / or pre-neoplastic lesions from repeated dose toxicity studies (subacute, subchronic, chronic) following oral or dermal exposure, a carcinogenicity study is not considered necessary. Based on all available data, Octopirox does not have to be classified accordingly.
Additional information
The following information is taken into account for the hazard / risk assessment:
Octopirox is considered to not exert any in vivo carcinogenic effect by any route of exposure based on the absence of genotoxic or mutagenic properties and the absence of the induction of hyperplastic or pre-neoplastic lesions in repeated dose toxicity studies (subacute, subchronic, chronic). No indications of a carcinogenic potential exists.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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