2,2'-azobis[2-methylbutyronitrile]

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: This study was selected as the key study because the information provided for the hazard endpoint is sufficient for the purpose of classification and labeling and/or risk assessment.

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7840 (Water Solubility)

Deviations:

no

Remarks:

- The study was conducted according to the test guidelines in effect at the time of study conduct

GLP compliance:

yes

Type of method:

flask method

Water solubility:

>= 387 - <= 397 mg/L

Temp.:

20 °C

pH:

>= 6.18 - <= 6.64

Details on results:

The preliminary test to estimate the solubility of the test substance at 20 ± 0.5°C using the shake flask method gave an average solubility of 397 mg/L in reagent water.
In the definitive test, the test substance was determined to have a water solubility of 392 ± 5 mg/L in reagent water at 20 ± 0.5°C.

Abbreviated Sample ID	Concentration From Multichrom(µg/mL)	Dilution Factor	Test Substance Recovered(µg/mL)	Mean Recovery(µg/mL)	Percent Difference From Previous Time       point
DEF-24-DIL-A	118.66673	3.33	396
DEF-24-DIL-B	118.02392	3.33	393	395	N/A
DEF-48-DIL-A	115.30946	3.33	384
DEF-48-DIL-B	119.20998	3.33	397	391	-1.02
DEF-72-DIL-A	116.82906	3.33	389
DEF-72-DIL-B	116.94701	3.33	390	390	-0.256
		Overall Mean	392
		Std. Dev	5

Conclusions:

This study and the conclusions which are drawn from it fulfill the quality criteria (validity, reliability, repeatability).
The test substance was determined to have a water solubility of 392 ± 5 mg/L in reagent water at 20 ± 0.5°C.

Executive summary:

The test substance, according to the shake flask method, was determined to have a water solubility of 392 ± 5 mg/L in reagent water at 20 ± 0.5°C.

Description of key information

392 ± 5 mg/L in reagent water at 20 ± 0.5°C

Key value for chemical safety assessment

Water solubility:

392 mg/L

at the temperature of:

20 °C

Additional information

EPA OPPTS 830.7840, flask method