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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: This study was selected as the key study because the information provided for the hazard endpoint is sufficient for the purpose of classification and labeling and/or risk assessment.
Qualifier:
according to
Guideline:
EPA OPPTS 830.7840 (Water Solubility)
Deviations:
no
Remarks:
- The study was conducted according to the test guidelines in effect at the time of study conduct
GLP compliance:
yes
Type of method:
flask method
Water solubility:
>= 387 - <= 397 mg/L
Temp.:
20 °C
pH:
>= 6.18 - <= 6.64
Details on results:
The preliminary test to estimate the solubility of the test substance at 20 ± 0.5°C using the shake flask method gave an average solubility of 397 mg/L in reagent water.
In the definitive test, the test substance was determined to have a water solubility of 392 ± 5 mg/L in reagent water at 20 ± 0.5°C.

Abbreviated Sample ID

Concentration From Multichrom(µg/mL)

Dilution Factor

Test Substance Recovered(µg/mL)

Mean Recovery(µg/mL)

Percent Difference From Previous Time       point 

DEF-24-DIL-A

118.66673

3.33

396

 

 

DEF-24-DIL-B

118.02392

3.33

393

395

N/A

DEF-48-DIL-A

115.30946

3.33

384

 

 

DEF-48-DIL-B

119.20998

3.33

397

391

-1.02

DEF-72-DIL-A

116.82906

3.33

389

 

 

DEF-72-DIL-B

116.94701

3.33

390

390

-0.256

 

 

Overall Mean

392

 

 

 

 

Std. Dev

5

 

 

Conclusions:
This study and the conclusions which are drawn from it fulfill the quality criteria (validity, reliability, repeatability).
The test substance was determined to have a water solubility of 392 ± 5 mg/L in reagent water at 20 ± 0.5°C.
Executive summary:

The test substance, according to the shake flask method, was determined to have a water solubility of 392 ± 5 mg/L in reagent water at 20 ± 0.5°C.

Description of key information

392 ± 5 mg/L in reagent water at 20 ± 0.5°C

Key value for chemical safety assessment

Water solubility:
392 mg/L
at the temperature of:
20 °C

Additional information

EPA OPPTS 830.7840, flask method