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EC number: 204-688-5 | CAS number: 124-19-6
The test substance was assessed for skin and eye irritation. There was potential for skin irritation, according to Regulation 67/548/EEC (DSD). There was no potential for eye irritation.
Table 1: Individual ocular scores
Time after administration
Animal No. 6408F
Animal No. 6409M
Animal No. 6410F
Animal No. 6411M
Animal No. 6412F
Animal No. 6415M
Animal No. 6414Fb
Animal No. 6417Mb
Animal No. 6418Fb
F: Observation confirmed with fluorescein
b: Both eyes were rinsed for one minute with lukewarm water 20 seconds after dosing
The key study report indicated that the test material was irritating to skin as the mean erythema score was 2.0 in all 4 animals which was equal to the threshold value of 2.0 under Regulation 67/548/EEC. Within the framework of Regulation (EC) No. 1272/2008, which uses a threshold of 2.3 rather than 2.0, this result is negative.
In the key study, the test substance was found not to be irritating to eyes.
Justification for selection of skin irritation / corrosion endpoint: Key study that meets generally accepted scientific standards, well documented and acceptable for assessment. Justification for selection of eye irritation endpoint: Key study performed according to a guideline, with acceptable restrictions. Effects on skin irritation/corrosion: irritating
The test substance was assessed for skin and eye irritation. There was no potential for skin irritation within the framework of Regulation (EC) No. 1272/2008 (CLP), however in accordance with Regulation 67/548/EEC the test substance is classified as a skin irritant.
There was no potential for eye irritation.
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