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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Reference
Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Qualifier:
according to guideline
Guideline:
OECD Guideline 201 (Alga, Growth Inhibition Test)
GLP compliance:
yes
Analytical monitoring:
yes
Test organisms (species):
Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum)
Details on test organisms:
ATCC 22662
Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
96 h
Hardness:
The determination was carried out in media with two hardnesses; the standard medium with a hardness of 15 mg/L CaCO3, and a medium with the hardness increased to 150 mg/L CaCO3.
Nominal and measured concentrations:
The concentrations; of Zinc-(L)-Lactate tested in low hardness medium were O, 32, 64, 130,260, 520, and 1040 µg/L. The concentrations of Zinc-(L)-lactate tested in high hardness medium were 0, 64, 130, 260, 520, 1040 and 2079 mg/L. The analytical measurement of zinc confirmed the initial test substance concentrations with a mean analytical recovery of 89 % (range 82-94 %).
Duration:
96 h
Dose descriptor:
EC50
Effect conc.:
0.52 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth rate
Remarks on result:
other: low hardness
Duration:
96 h
Dose descriptor:
EC50
Effect conc.:
2.1 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth rate
Remarks on result:
other: high hardness
Duration:
96 h
Dose descriptor:
EC10
Effect conc.:
216 µg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Basis for effect:
growth rate
Remarks on result:
other: low hardness
Duration:
96 h
Dose descriptor:
EC10
Effect conc.:
532 µg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Basis for effect:
growth rate
Remarks on result:
other: high hardness
Validity criteria fulfilled:
yes
Conclusions:
ErC50 = 0.52 mg/L
Executive summary:

ErC50 = 0.52 mg/L

Description of key information

Key value for chemical safety assessment

EC50 for freshwater algae:
0.52 mg/L
EC10 or NOEC for freshwater algae:
0.216 mg/L

Additional information