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EC number: 941-376-4 | CAS number: 147977-79-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
No effects up to the limit of water solubility (OECD 202).
Key value for chemical safety assessment
Additional information
Since no studies investigating the short-term toxicity of fatty acids, tall-oil, triesters with trimethylolpropane (CAS 94581-09-6) to aquatic invertebrates are available for this endpoint, in accordance to Regulation (EC) No 1907/2006 Annex XI, 1.5 a read across to the structurally related source substances Fatty acids, C16-18 and C18 unsatd., triesters with trimethylolpropane (CAS 68002-78-8), Fatty acids, C16-18 (even numbered) and C16-18-unsatd. (even numbered), triesters with trimethylolpropane (CAS 68002-79-9), 2-ethyl-2-(((1-oxoisooctadecyl)oxy)methyl)-1,3-propanediyl bis(isooctadecanoate) (CAS 68541-50-4) and fatty acids, C16-18 and C18-unsatd., branched and linear ester with trimethylolpropane (CAS 403507-18-6) was conducted. This read-across is justified in detail in the overall summary (IUCLID section 6.1) and within the analogue justification in IUCLID Section 13. In this case of read-across, the best suited (highest degree of structural similarity, nearest physico-chemical properties) read-across substances were used for the assessment.
The first study with the read-across substance fatty acids, C16-18 and C18-unsatd., triesters with trimethylolpropane (CAS 68002-78-8) was performed according to OECD 202 (Bouillon, 2012). Daphnia magna was exposed to the test substance in a static test system for 48 hours. The test was performed as a limit test with a loading ratio of 0.106 g (substance)/1000 g (test medium). An EL50 >106 mg/L based on the nominal concentration of the water accommodated fraction of the test substance was reported.
The second study with the read-across substance fatty acids, C16-18 (even numbered) and C16-18-unsatd. (even numbered), triesters with trimethylolpropane (CAS 68002-79-9). This study was performed according to OECD 202 (Gode & Mühlberg, 2002). No effects on mobility were observed and an EC50 (48 h) > 1000 mg/L (nominal) was determined.
The third study with the read-across substance 2-ethyl-2-(((1-oxoisooctadecyl)oxy)methyl)-1,3-propanediyl bis(isooctadecanoate) (CAS 68541-50-4). The study was performed according to OECD 202 (Marshall, 1996) with measured test concentrations up to 7.6 mg/L (measured). No effects on mobility were observed after 48 h resulting in an EC50 (48 h) > 7.6 mg/L.
The fourth study with the read-across substance fatty acids, C16-18 and C18-unsatd., branched and linear ester with trimethylolpropane (CAS 403507-18-6) was performed according to OECD 202 (GLP) using the water flea Daphnia magna (Wetton and McKenzie, 2004). Daphnids were exposed to a nominal limit concentration of 0.2 mg/L prepared in acetone. This concentration reflects the maximum concentration soluble in water. Preliminary experiments which are documented in the study report showed that higher concentrations lead to turbid test solutions which may affect the outcome of the study (e.g. physical effects by insoluble particles). The test substance concentration was verified analytically by HPLC/UV-Vis. After an exposure of 48 h no mortality was observed neither in the treatment nor in the solvent and test medium control resulting in an EC50 (48 h) of > 0.2 mg/L (nominal) and > 0.095 mg/L (meas. TWA).
Based on the available experimental studies from four structurally related read-across substances (in accordance to Regulation (EC) No 1907/2006 Annex XI, 1.5) which are characterized by a similar ecotoxicological profile and comparable structure, it can be concluded that fatty acids, tall-oil, triesters with trimethylolpropane (CAS 94581-09-6) will not exhibit short-term effects on aquatic invertebrates up to the limit of water solubility.
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