Registration Dossier

Toxicological information

Acute Toxicity: inhalation

Currently viewing:

Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
1976
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment
Remarks:
The study was conducted according to a generally accepted protocol, but not in compliance with GLP and with insufficient reporting of results.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1976
Report date:
1976

Materials and methods

Test guideline
Qualifier:
no guideline followed
GLP compliance:
no
Test type:
fixed concentration procedure
Limit test:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
3-(triethoxysilyl)propanethiol
EC Number:
238-883-1
EC Name:
3-(triethoxysilyl)propanethiol
Cas Number:
14814-09-6
Molecular formula:
C9H22O3SSi
IUPAC Name:
3-(triethoxysilyl)propanethiol

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
inhalation: vapour
Type of inhalation exposure:
whole body
Vehicle:
air
Analytical verification of test atmosphere concentrations:
no
Duration of exposure:
8 h
Concentrations:
'Concentrated vapour'.
No. of animals per sex per dose:
6
Control animals:
no

Results and discussion

Any other information on results incl. tables

No hazard is anticipated from the infrequent inhalation of substantially saturated vapour generated at room temperature under normal handling conditions.

Applicant's summary and conclusion

Interpretation of results:
study cannot be used for classification
Conclusions:
No deaths were reported in an 8 hour exposure to 'substantially saturated vapour', in a study the reliability of which could not be determined due to insufficient detail.