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Ecotoxicological information

Short-term toxicity to fish

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Description of key information

(96-h) LC50: 439 mg/l mortality in Brachydanio rerio (read-across from CAS 4420-74-0).

A stepwise testing strategy is proposed to address the requirements of the ECHA draft decision. Please refer to the attachment in Section 13. This read-across is retained as an interim measure to calculate a PNEC and support the existing chemical safety assessment until new evidence becomes available.

Key value for chemical safety assessment

LC50 for freshwater fish:
439 mg/L

Additional information

There are no data for the substance. However a 96-h LC50 value of 439 mg/l and NOEC of 350 mg/l have been determined for the effects of a structurally analogous substance, 3-trimethoxysilylpropane-1-thiol (CAS 4420 -74 -0) on mortality of Brachydanio rerio based on nominal concentrations of the substance according to EU C.1. The test substance is susceptible to very rapid hydrolysis and it is therefore likely that, under the conditions of the study, the test organisms were primarily exposed to the hydrolysis products of the substance.

Although this value is above the water solubility of the parent registered substance, the read-across is considered valid as the exposure was related to the hydrolysis product.